Material Feeders
![Medchemexpress LLC 2(1H)-Quinolinone, 6-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-methyl- | 140841-32-3 | 99.9% | 397.44 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000365616-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 2(1H)-Quinolinone, 6-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-methyl- | 140841-32-3 | 99.9% | 397.44 | 10 MG
ZD 2138 is identified as 2(1H)-Quinolinone, 6-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-methyl-. It has a molecular formula of C23H24FNO4 and a molecular weight of 397.44. This compound is typically an off-white to light yellow solid with a high purity of 99.9% confirmed by LCMS.
- High purity (99.9%) confirmed by LCMS.
- Consistent structure verified by 1H NMR spectrum.
- Available as an off-white to light yellow solid.
- Stable for extended periods under specified storage conditions.
- For research use only.
Cayman Chemical ZD 7155hydrochlorIde 5mg
An AT1 receptor antagonist (IC50 = 3.3 nM); inhibits angiotensin II-induced pressor responses in conscious normotensive rats; decreases mean arterial pressure in conscious spontaneously hypertensive rats at 1.082 µmol/kg; improves motor nerve conduction velocity in the sciatic nerve in a rat model of streptozotocin-induced diabetic neuropathy at 10 mg/kg in the drinking water; decreases disease severity and NF-κB and AP-1 activation in a mouse model of LPS-induced acute lung injury at 10 mg/kg
Cayman Chemical ZD 7155hydrochlorIde 25mg
An AT1 receptor antagonist (IC50 = 3.3 nM); inhibits angiotensin II-induced pressor responses in conscious normotensive rats; decreases mean arterial pressure in conscious spontaneously hypertensive rats at 1.082 µmol/kg; improves motor nerve conduction velocity in the sciatic nerve in a rat model of streptozotocin-induced diabetic neuropathy at 10 mg/kg in the drinking water; decreases disease severity and NF-κB and AP-1 activation in a mouse model of LPS-induced acute lung injury at 10 mg/kg
Apexbio Technology LLC ZD 7288(Synonyms: ZD7288, Zatebradine hydrochloride, HCN channel inhibitor ZD7288), 10mg, CAS: 133059-99-1.
ZD 7288 (CAS 133059-99-1) is a selective inhibitor of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels These channels mediate Na and K currents notably the hyperpolarization-activated current (I h) contributing to neuronal excitability and rhythmic activity ZD 7288 reduces I h in a concentration-dependent voltage- and time-sensitive manner as demonstrated in rat facial motoneurons (IC 50 0 2 M) and hippocampal CA1 pyramidal neurons Additionally it inhibits T-type calcium currents in rat CA1 pyramidal cells ZD 7288 is utilized in research investigating neuronal excitability mechanisms pain signaling and chronic visceral pain models
Apexbio Technology LLC ZD 7288(Synonyms: ZD7288, Zatebradine hydrochloride, HCN channel inhibitor ZD7288), 25mg, CAS: 133059-99-1.
ZD 7288 (CAS 133059-99-1) is a selective inhibitor of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels These channels mediate Na and K currents notably the hyperpolarization-activated current (I h) contributing to neuronal excitability and rhythmic activity ZD 7288 reduces I h in a concentration-dependent voltage- and time-sensitive manner as demonstrated in rat facial motoneurons (IC 50 0 2 M) and hippocampal CA1 pyramidal neurons Additionally it inhibits T-type calcium currents in rat CA1 pyramidal cells ZD 7288 is utilized in research investigating neuronal excitability mechanisms pain signaling and chronic visceral pain models
Medchemexpress LLC ZD-4190 10mM 1mL | 1mL
ZD-4190 is a potent orally available inhibitor of the vascular endothelial cell growth factor receptor 2 (VEGFR2) and of epidermal growth factor receptor (EGFR) signalling used for the treatment of cancer
Cayman Chemical ZD 7155hydrochlorIde 1mg
An AT1 receptor antagonist (IC50 = 3.3 nM); inhibits angiotensin II-induced pressor responses in conscious normotensive rats; decreases mean arterial pressure in conscious spontaneously hypertensive rats at 1.082 µmol/kg; improves motor nerve conduction velocity in the sciatic nerve in a rat model of streptozotocin-induced diabetic neuropathy at 10 mg/kg in the drinking water; decreases disease severity and NF-κB and AP-1 activation in a mouse model of LPS-induced acute lung injury at 10 mg/kg
TARGETMOL CHEMICALS INC ZD 7155 HYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 receptor) antagonist. purity: 99%